Genesis 1:26-27 (ESV)
Then God said, “Let us make man in our image, after our likeness. And let them have dominion over the fish of the sea and over the birds of the heavens and over the livestock and over all the earth and over every creeping thing that creeps on the earth.”
 So God created man in his own image,
in the image of God he created him;
male and female he created them.
We are created as male or female. The attempts at running away from God now include denying that. This story from the Toronto Star last Saturday. A couple are seeking to raise a “genderless” baby. I am sure even they know that their baby has a gender. But they don’t want it to be known. Read a bunch of responses there as well, both in support and criticism.
Read a Christian critique here